For treatment of diabetes, Galvus (vildagliptin), manufactured by Novartis, works to improve pancreatic function in patients with type 2 diabetes. The key ingredient, vildagliptin, supports incretin hormones which stimulate the pancreas, allowing it to produce more insulin to counter rising levels of blood glucose. It also reduces the liver’s glucose production with the increased insulin and decreased levels of the glucagon hormone. For treating diabetes, Galvus was first approved in 2008 by the European Medicines Agency for use in the European Union, in combination with other oral anti-diabetes drugs such as metformin. In 2012, it was approved in China. Galvus is now used in over 90 countries in Europe, Africa, Asia Pacific and Latin America. However, Galvus has not been approved by the Food and Drug Administration (FDA) for use in the U.S. In 2007, the FDA requested additional clinical data about possible issues with kidney impairment and skin lesions. In 2008, Novartis withdrew its request for FDA approval. In studies examining its efficiency in reducing the high blood sugar of diabetes, Galvus was shown to be most effective when combined with an existing diabetes treatment, and not as effective on its own or when combined with insulin therapy.
Galvus Side Effects and Contraindications
When considering drugs for treating diabetes, Galvus should not be used by patients with severe heart disease, and those with liver problems should be tested before and while taking Galvus, since there is a known connection between vildagliptin and the risk of liver disease. Patients who may be advised not to take Galvus include those with heart, kidney or liver conditions, galactose intolerance or glucose-galactose absorption issues, skin problems like ulcers, and people who require insulin. The more common side effects caused by Galvus are dizziness, headaches, nausea, decreased blood sugar, weakness, tremors, and weight gain (when combined with a glitazone drug). Galvus is only intended for adults with type 2 diabetes, and should not be used by women who are pregnant or are breastfeeding.
Find Galvus Alternatives
Be wary of internet advertisements for Galvus without a prescription. Given the possible side effects, this medication should only be used under a doctor’s care. There are other options you should consider for treating your diabetes. Galvus, taken with another medication such as metformin, should be considered only when other treatments fail. A safe and effective way to treat high blood sugar and the symptoms of diabetes involves lifestyle changes. This includes eating a healthy diet of fiber-rich fruits and vegetables, whole grains, beans and legumes, nuts and healthy omega-3 and olive oils. It is recommended that you drink 8 glasses of water a day, and include daily exercise as part of your healthy regime. You should quit smoking and at least cut back on alcohol consumption to keep yourself healthy and free of diabetes symptoms.
