Used to treat Type 2 diabetes, Avandamet, manufactured by GlaxoSmithKline, was approved by the U.S. Food and Drug Administration (FDA) in 2002. It combines two of the most popular diabetes medications, metformin hydrochloride and rosiglitazone maleate. The rosiglitazone improves insulin sensitivity, while the metformin reduces the liver’s glucose production, and also decreases the body’s sugar absorption from foods. It does not increase the amount of insulin produced, but makes better use of the insulin already there. Combined together to treat diabetes, Avandamet is believed to be a more effective control of blood sugar levels in the body, and is also helpful in increasing “good cholesterol” and reducing “bad cholesterol.” However, in 2011, serious health concerns caused the company to recall the drug from retail pharmacies, and it is now only available through certified pharmacies by mail order.
Avandamet Side Effects and Recall
The milder side effects that may occur with the use of diabetes Avandamet medication are upset stomach, headaches, and upper respiratory infections. Lactic acidosis may be another side effect, with symptoms such as nausea with vomiting, stomach pain, muscle pain or weakness, numbness in arms and legs, dizziness, weakness or trouble breathing. More serious Avandamet risks are increased likelihood of heart attack or stroke, and those with heart or kidney disease, or diabetic ketoacidosis, are advised not to take Avandamet. In September 2010, The FDA announced the restriction of this treatment for diabetes, Avandamet, due to “cardiovascular events” such as strokes and heart attacks brought about by the use of rosiglitazone, one of Avandamet’s ingredients. This had been a concern as early as 2007. The drug was taken out of pharmacies and is now sold by mail order only to certain pre-screened patients who are not able to control their diabetes in any other way. This “restricted access” applies to all drugs that contain rosiglitazone.
Avandamet Alternatives for Healthier Treatment
Since Avandamet is now only approved for those who cannot be successfully treated by any other means, there are many alternatives which should be considered. The most important treatment program for all diabetics, whether they are taking medications or not, is to make a lifestyle change to include a healthy, balanced diet, regular exercise, and weight loss. Sometimes, ridding oneself of toxic poisons such as processed foods, unhealthy fats and sugars is enough to reverse the progression of diabetes. Avandamet, with its risks and dangers, should not have to be considered as a viable treatment option for anyone. A healthy diet begins with nutritious fruits and vegetables, nuts, whole grains, and “good fats” (e.g. omega-3 and olive oils, nuts), and sufficient water intake every day (8 glasses). If you’re a smoker, quit immediately, and drastically cut down (or cut out) alcohol consumption for optimal health.
