DHEA (dehydroepiandrosterone) is a naturally occurring steroidal hormone in the body, produced by the adrenal gland, which is converted into the male and female sex hormones. A possible connection between DHEA and diabetes was not considered until recently. It was believed that the only function of DHEA was to create testosterone and estrogen, but recent research has shown that it’s involved in many functions, possibly even to help prevent cancer. It has been referred to as the “anti-aging hormone.” DHEA supplements were popular in the 1980s, marketed for anti-aging and weight loss. The Food and Drug Administration prohibited its sale for several years, citing a lack of research on long-term effects. A change in laws brought it back as a supplement in 1994, and there have been numerous studies since then, showing its cancer fighting qualities and other uses, including the connection between DHEA and diabetes. DHEA is synthesized from wild yam and soy. It cannot be produced by the body from those foods, so it must be taken in supplement form. Today, DHEA is used to slow aging, increase strength, treat osteoporosis and multiple sclerosis, cure depression, and slow down the process of Alzheimer’s disease. In the case of DHEA and diabetes, DHEA levels are found to be low in those with type 2 diabetes. A study conducted by Dr. Dennis T. Villareal, assistant professor of geriatrics and nutritional science at Washington University in St. Louis, found that DHEA supplementation reduced abdominal fat and improved insulin sensitivity [http://www.defeatdiabetes.org/Articles/hormone041201.htm].
Diabetes, DHEA, and Possible Health Risks
DHEA is considered relatively safe when used short term (a few months), though it may be less safe in larger amounts and when used for longer periods of time. It is recommended that you do not take a dosage greater than 50-100 mg a day. Short term side effects of DHEA may include stomach upset, high blood pressure, acne and hair loss. It may cause an increase of the male hormone androgen, so it is not recommended for women who are pregnant or breastfeeding. It may also cause facial growth and changes in menstrual cycle. Women who have a condition that may be worsened by exposure to estrogen shouldn’t use DHEA, and people with liver problems are also advised against using it. With regard to DHEA and diabetes, if you are taking DHEA to increase insulin sensitivity, you should monitor your blood sugar levels closely.
DHEA, Diabetes, and the Ongoing Debate
Before using this supplement, one must consider the pros and cons of DHEA and diabetes treatment. There have been many studies done, with the decision seemingly split between those who recommend DHEA for a number of issues, including weight reduction and as a diabetes treatment to improve insulin sensitivity, and those who believe the health risks outweigh the benefits. Research on this supplement is ongoing.
