Diabetes causes many complications, and macrovascular disease in diabetes is a major cause for concern. Of all the complications that arise with diabetes, macrovascular disease in diabetes are the set of diseases that lead to the most likely causes of death. When you look at these complications that make up the macrovascular disease diabetes category, it doesn’t take a doctor to realize just how serious macrovascular complications are. Coronary artery disease, peripheral arterial disease, and stroke are the result of long term diabetes type 2 that is not adequately controlled. These complications alone are responsible for tens of thousands of death yearly. Stroke is the third leading cause of death, and heart disease is number one on the list. Often times, macrovascular disease in diabetes is the underlying cause of stroke and heart failure ot heart attack. Controlling your type 2 diabetes is the best defense.