First introduced in 1984 as a sulfonylureas class of medication for the treatment of diabetes, glipizide is sold under the brand names of Glucotrol®, GlucotrolXL®, and Metaglip® (as a combination of Glipizide and Metformin). It is prescribed for type 2 diabetes to assist the pancreas in producing insulin, thereby lowering blood sugar, and increasing the body’s efficiency in using that insulin. Glipizide is not a diabetes cure. It can only work if a person is able to produce at least some insulin; therefore, it is not for use by those with type 1 diabetes. Glipizide is available in regular form and extended release, and is to be taken orally 30 minutes before meals to control blood sugar.

Glipizid and Diabetes: Weighing the Benefits against the Side Effects

There are dozens of medications that may interact with glipizide, such as aspirin and other anti-inflammatory drugs such as ibuprofen (Motrin, …